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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FYN All Species: 40.3
Human Site: S232 Identified Species: 88.67
UniProt: P06241 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06241 NP_002028.1 537 60762 S232 Q Q L V Q H Y S E R A A G L C
Chimpanzee Pan troglodytes XP_001158656 541 61057 S232 Q Q L V Q H Y S A L T S I I A
Rhesus Macaque Macaca mulatta XP_001085015 537 60711 S232 Q Q L V Q H Y S E R A A G L C
Dog Lupus familis XP_854467 537 60713 S232 Q Q L V Q H Y S E R A A G L C
Cat Felis silvestris
Mouse Mus musculus P39688 537 60637 S232 Q Q L V Q H Y S E R A A G L C
Rat Rattus norvegicus Q62844 537 60683 S232 Q Q L V Q H Y S E R A A G L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505504 656 73783 S354 Q Q L V Q H Y S E K A D G L C
Chicken Gallus gallus Q05876 534 60247 S232 Q Q L V Q H Y S E K A D G L C
Frog Xenopus laevis P13406 537 60828 S232 Q Q L V Q H Y S E R A A G L C
Zebra Danio Brachydanio rerio NP_001025140 544 61022 T239 Q Q L V Q H Y T E R A A G L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 T237 T E G L S H R T R D Q W E I D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.6 99.8 N.A. 99 99.6 N.A. 70.1 92.3 96.8 90.6 N.A. 54.5 N.A. N.A. N.A.
Protein Similarity: 100 98.8 99.8 99.8 N.A. 99.6 99.6 N.A. 73.3 94.4 98.1 95.2 N.A. 68.1 N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 100 N.A. 100 100 N.A. 86.6 86.6 100 93.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 100 100 N.A. 93.3 93.3 100 100 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 82 64 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 19 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 82 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 82 0 0 % G
% His: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 19 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % K
% Leu: 0 0 91 10 0 0 0 0 0 10 0 0 0 82 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 91 91 0 0 91 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 64 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 0 82 0 0 0 10 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % T
% Val: 0 0 0 91 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _